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디바비바 필러 52주 임상 논문 SCI급 국제학술지 게재

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작성자 Juventa 댓글 8case 조회 1,997view 작성일 21-05-24 13:22

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유벤타헬스케어는 히알루론산 필러 ‘디바비바’ 임상 논문이 Journal of Cosmetic Dermatology, JCD 국제학술지에 게재됐다고 12일 밝혔다. 해당 논문에서 디바비바의 팔자 주름 개선에 대한 효능 및 안전성이 입증됐다. 유벤타헬스케어 관계자는 “이번 임상시험의 국제학술지 게재는 52주 임상 결과라는 점에서 의미가 크다”며 “팔자 주름 개선에 있어 외산 필러와 비교했을 때 동등한 효과를 보인다는 것을 객관적으로 입증했다”고 말했다.

이번 임상은 중증 이상의 팔자주름으로 교정이 요구되는 성인 106명을 대상으로 이뤄졌다. 연구는 무작위배정방법에 따라 피험자 안면중앙부의 우측 및 좌측에 ‘디비바바 미디움(DIVAVIVA medium)’, 대조군 필러 ‘제품 R’을 각각 주사하는 방식으로 진행됐다.

그 결과, 미용 만족도 평가인 GAIS(Global Aesthetic Improvement Scale)평가에 있어 조사자와 피험자 자체 평가 모두에서 개선이 있었다. 피험자의 경우 디바비바 미디움 2주차에 100%, 52주차에 평균 37.8% 비율로 개선, 제품 R은 2주차에 100%, 52주차에 34.1% 비율로 개선이 있었다고 평가했다. 디바비바 미디움, 제품 R 두 그룹간 통계적으로 유의한 차이가 없었다. 

주름 심각도 척도 등급 WSRS(Wrinkle Severity Rating Scale)에서 1개 등급 이상 감소한 피시험자 비율에 있어서도 평가자의 평가의 경우 디바비바 미디움은 2주차에 100%, 52주차에 41.5%, 제품 R은 2주차에 100%, 52주차에 40.2% 비율로 WSRS 등급이 1개 등급 이상 감소했다고 평가했다. 이 역시 디바비바 미디움, 제품 R 두 그룹간 통계적으로 유의한 차이가 없었다. 또한 안전성에 있어서 피험자들은 특별한 이상 반응을 보이지 않았다.

한편, 디바비바는 유영제약에서 제조한 히알루론산 필러로 유영제약 BH(Beauty & Healthcare) 사업본부의 분할을 통해 설립한 유벤타헬스케어에서 판매중이다. 베리굿 조현이 디바비바 모델로 활약하고 있으며, 향후 국내외 업체들과 해외 사업도 확대할 계획이다.

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